A new chapter in Introductory Organic Chemistry course. Lecture PowerPoint file and laboratory document are also included in this work. The goal of this chapter is to cover the basic ground of the food additives from the perspective of organic chemistry. This chapter has three parts. Part one: Introduction of the food additive industry including the history, definition and the purposes of food additives. Part two: The terminology in food additives and in organic chemistry, how to locate trustworthy data sheets for chemicals, and how to interpret the toxicity data. Part three: Different families of organic compounds used as food additives in modern food industry, discussions about their structures, chemical properties and health concerns. Lecture PowerPoint slides have all in-class questions/discussions and after-class assignments listed. Laboratory document ‰ÛÒ Synthesis of Yellow 5 (Sunset yellow), an Azo dye used in food industry. Document includes a short introduction, detailed experimental procedure and post-laboratory questions.